James X. Hartmann
- Ph.D., Michigan State University, 1972
- Immunotherapy of cancer
- Regulation of the immune system
- Inflammatory and autoimmune diseases
My lab studies cells of the immune system such as dendritic, macrophage, T helper and T cytotoxic cells to determine how they interact to cause inflammatory and autoimmune diseases such as asthma. We also attempt to find means to activate immune cells so they selectively destroy cancer cells. Our recent focus has been on the role of vitamin D in preventing/treating asthma. We are currently focusing on rendering cancer cells highly visible or immunogenic to dendritic cells.
- Padilla, A., Keating, P., Hartmann, J. X., & Marí, F. 2017. Effects of α-conotoxin ImI on TNF-α, IL-8 and TGF-β expression by human macrophage-like cells derived from THP-1 pre-monocytic leukemic cells. Scientific reports. 7(1):12742.
- Keating, P., & Hartmann, J. X. 2017. Isolation and Purification of Th9 Cells for the Study of Inflammatory Diseases in Research and Clinical Settings. Th9 Cells: Methods and Protocols. 247-255.
- Kats, A, Pavlovic, M, Chen, R, Cavallo,M & J Hartmann. 2017. Comparison and Analysis of Different Methods for Purification of Autoimmune Antibody Reactive with Single-Stranded DNA: A Pilot Study. MoJ Proteonomics Bioinformatics. 5(3):00161.
- Chen, R. Pavlovic M, Cavallo, M, Kats,A & Hartmann JX. 2016. Two Step Magnetic Beads Based Purification Method for Antibody Reactive with Single-Stranded DNA: A pilot study. MoJauto Dis. 1(1):00004.